Progesterone is beneficial because it lightens periods. It also reduces inflammation, regulates immune function, and supports healthy thyroid, brain, bones, and breasts.
Do you make enough progesterone? Are you sure?
The only way to make progesterone is with ovulation and a healthy luteal phase.
According to a new Lancet review paper, menstrual migraines are more severe than migraines at other times of the cycle.
The authors of the paper explain that menstrual migraines are caused by estrogen withdrawal at the end of the cycle together with an estrogen-dependent release of prostaglandins and histamine. They propose progesterone as a possible prevention strategy.
Period pain or dysmenorrhea should be mild and respond to simple treatments like ibuprofen, zinc, or a dairy-free diet. If period pain does not respond to simple treatments, it could be endometriosis or adenomyosis.
Debilitating period pain is never normal.
Mast cell activation and histamine can play a role in premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD).
That’s why mid-cycle, premenstrual, and perimenopausal mood symptoms can be relieved by antihistamines and natural histamine-reducing strategies such as vitamin B6, SAM-e, and a dairy-free diet.
Endometriosis is not a hormonal condition. It’s affected by estrogen but is not caused by estrogen or “estrogen dominance.”
Instead, endometriosis is a whole-body inflammatory and immune disease, and possibly a microbial disease.
What does that mean for treatment?
Progesterone is usually soothing to mood but can sometimes cause anxiety. A negative mood reaction to progesterone is called neurosteroid change sensitivity or premenstrual dysphoric disorder (PMDD) and affects about one in twenty women.
Here’s everything you need to know about progesterone and mood.