Why Progesterone Is Both Good and Bad for Mood (and How to Treat PMDD)

Mood effects of progesterone.

Progesterone is usually soothing to mood but can sometimes cause anxiety.

A negative mood reaction to changing levels of progesterone is called neurosteroid change sensitivity or premenstrual dysphoric disorder (PMDD) and affects about one in twenty women.

Also, see Top 6 natural treatments for premenstrual mood symptoms.

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Natural Treatment of Menstrual Migraines

menstrual migraines

According to a Lancet review paper, menstrual migraines are more severe than migraines at other times of the cycle.

Possible drivers of menstrual migraines include estrogen withdrawal at the end of the cycle, plus an estrogen-dependent release of prostaglandins and histamine. Body-identical progesterone may help to shelter the brain from estrogen withdrawal and reduce the frequency and intensity of menstrual migraines.

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Why I Prescribe Iodine for Breast Pain, Ovarian Cysts, and PMDD

iodine for women's health

Iodine can relieve breast pain, ovulation pain, premenstrual mood symptoms and help to prevent ovarian cysts. It works by promoting healthy estrogen metabolism, down-regulating estrogen receptors, and stabilizing estrogen-sensitive tissue in the breasts, uterus, ovaries, and brain. As one paper says, iodine has “a net anti-estrogenic effect.”

Iodine’s anti-estrogen effect makes it one of the best treatments for estrogen excess or “estrogen dominance”—although I don’t use that term.

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Taurine: 5 Benefits for Women’s Health

Taurine for women's health

Taurine is one of my favorite prescriptions for perimenopause, menopause, sleep, mood, insulin resistance, and migraine prevention.

Taurine is an amino acid, but unlike most amino acids, it doesn’t build protein. Instead, taurine has directly beneficial effects on the liver, brain, mitochondria, immune system, and nervous system. Taurine is so important that it makes up about 0.1 percent of total body weight.

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