Tried B6 for PMS/PMDD, but it caused anxiety. Is this normal?
Posted: Mon Jan 24, 2022 7:56 am
Hi all,
I've had success with magnesium and vitex for mood symptoms during PMS (yay!). After recently re-reading the PMS section in Lara's Period Repair Manual book I noticed that B6 is the 2nd best supplement for PMS, so I decided to give it a go. I purchased 50mg of b6 in the P5P form, the lowest available dose at the stores I visited.
After a few days of supplementing, I felt highly anxious and found myself reacting anxiously to benign situations and being on edge in general. There were no stressful events at this time with work/home-life. I was still eating healthy (no new foods), exercising, and sleeping 8-9 hours & following my sleep schedule. I asked myself what had changed over the last week, and the only thing was adding the P5P. I decided to stop taking the supplement to see if it was the cause, and the anxiety went away gradually 2-3 days later. I did not try a re-challenge, but am considering it to confirm the cause.
I'm a bit confused as to why P5P caused me so much anxiety and what the mechanism might have been. I've read briefly about b6 toxicity and how some individuals can be extra sensitive, but didn't think this was possible with P5P. If you have a potential answer or experienced the same thing with P5P, I'd be happy to hear from you!
In case it's relevant, I had started the supplement at the start of my period, and got off prior to ovulation (so the anxiety was not PMS-related).
Side note, so cool there's now a forum
Thank you in advance for your thoughts!
I've had success with magnesium and vitex for mood symptoms during PMS (yay!). After recently re-reading the PMS section in Lara's Period Repair Manual book I noticed that B6 is the 2nd best supplement for PMS, so I decided to give it a go. I purchased 50mg of b6 in the P5P form, the lowest available dose at the stores I visited.
After a few days of supplementing, I felt highly anxious and found myself reacting anxiously to benign situations and being on edge in general. There were no stressful events at this time with work/home-life. I was still eating healthy (no new foods), exercising, and sleeping 8-9 hours & following my sleep schedule. I asked myself what had changed over the last week, and the only thing was adding the P5P. I decided to stop taking the supplement to see if it was the cause, and the anxiety went away gradually 2-3 days later. I did not try a re-challenge, but am considering it to confirm the cause.
I'm a bit confused as to why P5P caused me so much anxiety and what the mechanism might have been. I've read briefly about b6 toxicity and how some individuals can be extra sensitive, but didn't think this was possible with P5P. If you have a potential answer or experienced the same thing with P5P, I'd be happy to hear from you!
In case it's relevant, I had started the supplement at the start of my period, and got off prior to ovulation (so the anxiety was not PMS-related).
Side note, so cool there's now a forum
Thank you in advance for your thoughts!
