Natural Treatment of Menstrual Migraines

menstrual migraines

According to a new Lancet review paper, menstrual migraines are more severe than migraines at other times of the cycle.

The authors of the paper explain that menstrual migraines are caused by estrogen withdrawal at the end of the cycle together with an estrogen-dependent release of prostaglandins and histamine. They propose progesterone as a possible prevention strategy.

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The Role of Histamine and Mast Cells in PMS and PMDD

histamine and PMDD

Mast cell activation and histamine can play a role in premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). 

That’s why mid-cycle, premenstrual, and perimenopausal mood symptoms can be relieved by antihistamines and natural histamine-reducing strategies such as vitamin B6, SAM-e, and a dairy-free diet. 

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Why Progesterone Is Both Good and Bad for Mood (and How to Treat PMDD)

Mood effects of progesterone.Progesterone is usually soothing to mood but can sometimes cause anxiety. A negative mood reaction to progesterone is called neurosteroid change sensitivity or premenstrual dysphoric disorder (PMDD) and affects about one in twenty women.

Here’s everything you need to know about progesterone and mood.

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The Curious Link Between Estrogen, Mast Cells, and Histamine

The role of mast cells and histamine in estrogen dominanceHeadaches. Anxiety. Insomnia. Brain fog. Hives. Nasal congestion. These are just a few of the symptoms of mast cell activation or high histamine.

Histamine symptoms are more common in women and often track with the menstrual cycle, occurring when estrogen is high at ovulation and then again just before the period. 

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