Natural progesterone fared well in the new KEEPS study. It proved to be effective for menopausal symptoms, but without the risks of conventional HRT.
When I first started practicing in the 1990s, many of my patients needed a way off the nasty HRT duo of Premarin (horse estrone) and Provera (medroxyprogesterone). As the WHI study was to prove in 2002, those pseudo-hormones cause breast cancer and significant cardiovascular risk. My job as a natural doctor was to help women transition onto natural progesterone.