The Role of Histamine and Mast Cells in PMS and PMDD

histamine and PMDD

Mast cell activation and histamine can play a role in premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). 

That’s why mid-cycle, premenstrual, and perimenopausal mood symptoms can be relieved by antihistamines and natural histamine-reducing strategies such as vitamin B6, SAM-e, and a dairy-free diet. 

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The Dos and Don’ts of Vitex for Period Problems

Vitex or chastetree for period problems.Vitex (also called chaste tree or chasteberry) is a herbal medicine prepared from the berries of the Mediterranean tree Vitex agnus-castus. In ancient times, it was used to suppress the libido of monks, hence the name. Fortunately, it does not have that effect on women.

Vitex is effective medicine for breast pain, irregular periods, premenstrual mood symptoms, and some types of acne.

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The Curious Link Between Estrogen, Mast Cells, and Histamine

The role of mast cells and histamine in estrogen dominanceHeadaches. Anxiety. Insomnia. Brain fog. Hives. Nasal congestion. These are just a few of the symptoms of mast cell activation or high histamine.

Histamine symptoms are more common in women and often track with the menstrual cycle, occurring when estrogen is high at ovulation and then again just before the period. 

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What Dairy Does to Periods

cow's dairy and periodsMore than twenty years ago I discovered something: When I stopped having dairy, I stopped having period pain.

Since then, I’ve worked with thousands of patients who have had the same result. For many women (not all), stopping dairy can dramatically improve period pain, heavy periods, endometriosis, acne, and PMS.

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